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Photo by Angèle Kamp on Unsplash

As cloning techniques advanced and the isolation of specific genes was easier and cheaper new genes were expressed into bacteria or cell cultures. This showcased a problem, how to detect the new exogenous protein?. An Antibody is an option, but if the protein is novel. The antibody needs to be manufactured from scratch. And to manufacture an antibody large quantities of the protein are needed to immunize laboratory animals. Another option will be to ask around…